SEC FORM 3 SEC Form 3
FORM 3 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
 
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1. Name and Address of Reporting Person*
Pagano Anthony

(Last) (First) (Middle)
C/O BILLIONTOONE, INC.
1035 O'BRIEN DRIVE

(Street)
MENLO PARK CA 94025

(City) (State) (Zip)
2. Date of Event Requiring Statement (Month/Day/Year)
01/01/2026
3. Issuer Name and Ticker or Trading Symbol
BillionToOne, Inc. [ BLLN ]
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
checkbox checked Director 10% Owner
Officer (give title below) Other (specify below)
5. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
checkbox checked Form filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4) 2. Amount of Securities Beneficially Owned (Instr. 4) 3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5) 4. Nature of Indirect Beneficial Ownership (Instr. 5)
Table II - Derivative Securities Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4) 2. Date Exercisable and Expiration Date (Month/Day/Year) 3. Title and Amount of Securities Underlying Derivative Security (Instr. 4) 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5) 6. Nature of Indirect Beneficial Ownership (Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Explanation of Responses:
Remarks:
No securities are beneficially owned.
/s/ Thomas Lynch, Attorney-in-Fact 01/05/2026
** Signature of Reporting Person Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
billiontoone-powerofatto
GDSVF&H\11612772.1 POWER OF ATTORNEY The undersigned, hereby constitutes and appoints each of Thomas Patrick Lynch, Taylor Thomas Pollock, Elena Vespoli, Michael Tiab, Holly Glavinic, and Scott Stefan Paraker as the undersigned’s true and lawful attorneys-in-fact to: • prepare and execute, in the undersigned’s name and on the undersigned’s behalf, and submit to the U.S. Securities and Exchange Commission (the “SEC”), a Form ID and any other documents necessary or appropriate to obtain the required codes and passwords enabling the undersigned to make electronic filings with the SEC of reports required by rule or regulation of the SEC; • act as account administrator for the undersigned’s Electronic Data Gathering, Analysis, and Retrieval (“EDGAR”) account with the SEC and to do and perform any and all acts for and on behalf of the undersigned that may be necessary or desirable in connection with the management of the undersigned’s EDGAR account, including, but not limited to, making submissions on EDGAR; adding, removing and delegating authority to users, account administrators, and technical administrators; delegating authority to other EDGAR accounts to file on behalf of the undersigned, and to remove delegated authority; and generating new filing codes; • complete and execute Schedules 13D and 13G in accordance with Section 13 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), Forms 3, 4 and 5 in accordance with Section 16 of the Exchange Act and the rules thereunder, Form 144 under Rule 144 under the Securities Act of 1933 (“Rule 144”), and in each case the rules and regulations promulgated thereunder, or any successor laws and regulations, as a consequence of the undersigned’s ownership, acquisition or disposition of securities, and other forms and all amendments thereto as such attorneys-in-fact shall in their discretion determine to be required or advisable; and • do all acts necessary in order to file such forms with the Commission, any securities exchange or national association, and such other person or agency as the attorneys-in-fact shall deem appropriate. The undersigned hereby ratifies and confirms all that said attorneys-in-fact and agent shall do or cause to be done by virtue hereof. The undersigned acknowledges that the foregoing attorneys-in-fact, in serving in such capacity at the request of the undersigned, are not assuming any of the undersigned’s responsibilities to comply with Section 13 or Section 16 of the Exchange Act or Rule 144 or any other SEC rule or regulation. The undersigned hereby grants to each such attorney-in-fact full power and authority to do and perform any and every act and thing whatsoever requisite, necessary, or proper to be done in the exercise of any of the rights and powers herein granted, as fully to all intents and purposes as the undersigned might or could do if personally present, with full power of substitution or revocation, hereby ratifying and confirming all that each such attorney-in-fact, or each such attorney-in-fact’s substitute or substitutes, shall lawfully do or cause to be done by virtue of this power of attorney and the rights and powers herein granted. This Power of Attorney shall remain in full force and effect until the undersigned is no longer required to file Schedules 13D, 13G, Forms 3, 4 and 5 or Form 144 with respect to the undersigned’s holdings of and transactions in securities, unless earlier revoked by the undersigned in a signed writing delivered to the foregoing attorneys-in-fact.


 
GDSVF&H\11612772.1 IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to be executed on December 6, 2025. By: /s/ Anthony Pagano Name: Anthony Pagano